Dr. Gary Brittenham’s research characterizes the effects of malaria and other infections on anemia and iron homeostasis.
Dr. Brittenham has a long-standing collaboration with the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, involving both training and research. An NIH-supported International Malarial Anemia Research Training Program helped prepare Thai physicians and scientists for careers in basic and clinical research on the pathogenesis of severe malarial anemia. NIH-supported research projects have included studies on (i) the pathogenesis of severe malarial anemia, (ii) magnetic resonance imaging (MRI) studies of the neuropathology of severe malaria, and (iii) studies to examine the effects of acute infection with Plasmodium falciparum malaria on the absorption, pharmacokinetics and metabolism of iron. With support from the Institut Mérieux, we are currently evaluating a new method for the non-invasive detection of iron deficiency in areas in Thailand endemic for malaria and other infections.